Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8285675 | 0.81 | GRM5 (0.53) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL8307713 | 0.79 | GRIN2D (0.57) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL14592093 | 0.79 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2KMT2AMEN1OPRM1 | |
| SCHEMBL8995830 | 0.78 | NOS2 (0.46) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL23343777 | 0.78 | NOS2 (0.46) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL2614966 | 0.74 | KDM4E (0.46) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL9491676 | 0.73 | KDM4E (0.63) | LMNAKDM4EL3MBTL1MAOAMAOB | |
| SCHEMBL22728750 | 0.73 | KDM4E (0.63) | LMNAKDM4EL3MBTL1MAOAMAOB | |
| SCHEMBL8615700 | 0.72 | CYP1A2 (0.47) | LMNASMN1; SMN2KMT2AMEN1CYP1A2 | |
| SCHEMBL25268173 | 0.72 | CCR1 (0.36) | SMN1; SMN2KMT2AMEN1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015073-B1 | SMOKING, FLAVORED AND FOODSTUFF COMPOSITIONS | PHILIP MORRIS INCORPORATED (US) | 1983-05-18 | — | — | EP | claimed |
| US-4259969-A | HYDROXYALKYLPYRAZINES AND -PYRIDINES | PHILIP MORRIS INCORPORATED (US) | 1981-04-07 | — | — | US | claimed |
| EP-0015073-A1 | Smoking, flavored and foodstuff compositions | PHILIP MORRIS INCORPORATED (US) | 1980-09-03 | — | — | EP | claimed |
| US-4474819-A | Flavored foodstuffs | PHILIP MORRIS, INCORPORATED (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0015073-B1 | SMOKING, FLAVORED AND FOODSTUFF COMPOSITIONS | PHILIP MORRIS INCORPORATED (US) | 1983-05-18 | — | — | EP | disclosed |
| US-4259969-A | HYDROXYALKYLPYRAZINES AND -PYRIDINES | PHILIP MORRIS INCORPORATED (US) | 1981-04-07 | — | — | US | disclosed |
| EP-0015073-A1 | Smoking, flavored and foodstuff compositions | PHILIP MORRIS INCORPORATED (US) | 1980-09-03 | — | — | EP | disclosed |