Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083541 | 1.00 | ATM (0.35) | ATMCTSSCTSKPOLBFPR3 | |
| SCHEMBL11088568 | 0.88 | RORC (0.39) | ATMCTSSCTSKPOLBHDAC1 | |
| SCHEMBL11088574 | 0.88 | RORC (0.39) | ATMCTSSCTSKPOLBHDAC1 | |
| SCHEMBL11088569 | 0.88 | RORC (0.39) | ATMCTSSCTSKPOLBHDAC1 | |
| SCHEMBL11083551 | 0.81 | BRD4 (0.38) | ATMCTSSCTSKPOLBHDAC1 | |
| SCHEMBL16019036 | 0.80 | KEAP1 (0.37) | ATMPOLBHDAC1HDAC2 | |
| SCHEMBL7828421 | 0.79 | ATM (0.42) | ATMPOLB | |
| SCHEMBL8597022 | 0.79 | ATM (0.42) | ATMPOLB | |
| SCHEMBL11088546 | 0.78 | CYP17A1 (0.41) | ATMCTSSCTSKPOLB | |
| SCHEMBL11088548 | 0.78 | CYP17A1 (0.41) | ATMCTSSCTSKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |