Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088569 | 0.82 | RORC (0.39) | ATMCTSSCTSKHDAC1HDAC2 | |
| SCHEMBL11088568 | 0.82 | RORC (0.39) | ATMCTSSCTSKHDAC1HDAC2 | |
| SCHEMBL11088574 | 0.82 | RORC (0.39) | ATMCTSSCTSKHDAC1HDAC2 | |
| SCHEMBL11083550 | 0.81 | ATM (0.35) | ATMCTSSCTSKHDAC1HDAC2 | |
| SCHEMBL11083541 | 0.81 | ATM (0.35) | ATMCTSSCTSKHDAC1HDAC2 | |
| SCHEMBL16019036 | 0.80 | KEAP1 (0.37) | ATMHDAC1HDAC2KEAP1NFE2L2 | |
| SCHEMBL7828421 | 0.79 | ATM (0.42) | ATMPOLBMAPTPDE3ASLC22A6 | |
| SCHEMBL8597022 | 0.79 | ATM (0.42) | ATMPOLBMAPTPDE3ASLC22A6 | |
| SCHEMBL23414380 | 0.78 | HDAC1 (0.38) | ATMCTSSCTSKHDAC1HDAC2 | |
| Water SCHEMBL8600954 | 0.78 | ATM (0.42) | ATMCTSSCTSKPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464366-A | Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group | CIBA GEIGY CORPORATION (US) | 1984-08-07 | — | — | US | disclosed |