Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PRKDC | P78527 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176530 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HPGDPRKDCKDM4EHSD17B10 | |
| SCHEMBL11094917 | 0.81 | EGFR (0.71) | ALDH1A1HPGDPRKDCKDM4EHSD17B10 | |
| SCHEMBL1344376 | 0.79 | PRKDC (0.56) | ALDH1A1HPGDPRKDCKDM4EHSD17B10 | |
| SCHEMBL4163540 | 0.78 | ALDH1A1 (0.68) | SLC9A1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL12867821 | 0.77 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL11092361 | 0.75 | TNKS (0.50) | ALDH1A1HPGDKDM4EPOLBCYP1A2 | |
| SCHEMBL6964494 | 0.74 | PRKDC (0.49) | ALDH1A1HPGDPRKDCKDM4EHSD17B10 | |
| SCHEMBL3427191 | 0.74 | PRKDC (0.49) | SLC9A1ALDH1A1HPGDPRKDCKDM4E | |
| SCHEMBL30314634 | 0.74 | DHODH (0.46) | SLC9A1ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL742929 | 0.74 | KDM4E (0.44) | ALDH1A1HPGDKDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4448787-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1984-05-15 | — | — | US | disclosed |
| US-4304728-A | 2,6-DIHYDROXY-2,5-HEXADIENOIC ACID DERIVATIVES, ANTIHISTAMINE INTERMEDIATES | LILLY INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |