SCHEMBL1344376

SCHEMBL1344376

O=c1cc(-c2ccccc2)oc(-c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 3/20 0.56
EGFR P00533 1/20 0.55
SMN1; SMN2 Q16637 4/20 0.53
TP53 P04637 4/20 0.53
CYP3A4 P08684 4/20 0.53
CYP19A1 P11511 4/20 0.53
HPGD P15428 4/20 0.53
CYP1B1 Q16678 4/20 0.53
TNKS O95271 3/20 0.53
AR P10275 3/20 0.53
ABCB1 P08183 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
NPC1 O15118 2/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
RAB9A P51151 2/20 0.53
CA9 Q16790 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9179291 0.87 PLA2G2A (0.49) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL3427191 0.85 PRKDC (0.49) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL11085896 0.85 NQO1 (0.54) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL6964494 0.85 PRKDC (0.49) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL9204834 0.82 PRKDC (0.46) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL1176530 0.82 ALDH1A1 (0.58) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL11085347 0.80 PRKDC (0.45) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL14449832 0.80 PRKDC (0.45) PRKDCEGFRSMN1; SMN2TP53CYP3A4
SCHEMBL9618242 0.79 PDE4A (0.62) EGFRSMN1; SMN2TP53CYP3A4HPGD
SCHEMBL11084153 0.79 SLC9A1 (0.47) PRKDCEGFRSMN1; SMN2TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0969966-B1 POSITIVE-WORKING INFRARED RADIATION SENSITIVE COMPOSITION AND PRINTING PLATE AND IMAGING METHOD KODAK POLYCHROME GRAPHICS LLC (US) 2002-07-17 EP claimed
US-6083662-A DEVELOPMENT WITH ALKALI METAL SILICATE, THICKENER, PHOSPHATE ESTER AND/OR NONIONIC FLUOROSURFACTANT EASTMAN KODAK COMPANY 2000-07-04 US claimed
CN-118638103-A Pyran derivative and electroluminescent device thereof 西安欧得光电材料有限公司 2024-09-13 CN disclosed
EP-2185360-B1 MULTI-LAYER IMAGEABLE ELEMENT WITH IMPROVED PROPERTIES EASTMAN KODAK CO (US) 2016-03-16 EP disclosed
EP-2079586-B1 MULTI-LAYER IMAGEABLE ELEMENT WITH IMPROVED PROPERTIES EASTMAN KODAK CO (US) 2014-06-25 EP disclosed
US-8062827-B2 Multilayer positive-working imageable elements and their use EASTMAN KODAK COMPANY (US) 2011-11-22 US disclosed
EP-1976698-B1 MULTILAYER IMAGEABLE ELEMENT WITH IMPROVED CHEMICAL RESISTANCE EASTMAN KODAK CO (US) 2011-03-30 EP disclosed
US-20110045397-A1 CHARGE CONTROL AGENT AND RELATED ART KURODA KAZUYOSHI 2011-02-24 US disclosed
US-7824840-B2 polymeric binder provides the post-development bakeability of imaged elements while increasing imaging sensitivity (speed) and maintaining resistance to press chemicals; solvent resistance; lithographic printing plates EASTMAN KODAK COMPANY (US) 2010-11-02 US disclosed
EP-2185360-A1 MULTI-LAYER IMAGEABLE ELEMENT WITH IMPROVED PROPERTIES Eastman Kodak Company (US) 2010-05-19 EP disclosed
US-20100035184-A1 MULTILAYER POSITIVE-WORKING IMAGEABLE ELEMENTS AND THEIR USE KODAK (NEAR EAST) INC. 2010-02-11 US disclosed
EP-0400706-B1 Dyes and dye-donor elements for use in thermal dye sublimation transfer AGFA GEVAERT NV (BE) 1994-07-13 EP disclosed
US-5142089-A Dyes and dye-donor elements for use in thermal dye sublimation transfer AGFA-GEVAERT, N.V. (BE) 1992-08-25 US disclosed
US-5026677-A Dyes and dye-donor elements for use in thermal dye sublimation transfer AGFA-GEVAERT, N.V. (BE) 1991-06-25 US disclosed
EP-0400706-A1 Dyes and dye-donor elements for use in thermal dye sublimation transfer AGFA-GEVAERT N.V. (BE) 1990-12-05 EP disclosed
US-4751073-A SUNSCREENS OLIN CORPORATION (US) 1988-06-14 US disclosed
US-4663260-A SEMICONDUCTOR LASER WAVELENGTHS FUJI PHOTO FILM CO., LTD. (JP) 1987-05-05 US disclosed
US-4341894-A 2,4,6 TRI-SUBSTITUTED PYRYLIUM DYE SALTS EASTMAN KODAK COMPANY (US) 1982-07-27 US disclosed
US-4167412-A COMPRISING A PYRYLIUM OR THIOPYRYLIUM SALT EASTMAN KODAK COMPANY (US) 1979-09-11 US disclosed
US-3938994-A Pyrylium dyes for electrophotographic composition and element EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed