Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344376 | 0.85 | PRKDC (0.56) | PRKDCSMN1; SMN2MAPTCYP19A1FTO | |
| SCHEMBL1176530 | 0.77 | ALDH1A1 (0.58) | PRKDCSMN1; SMN2MAPTCYP19A1FTO | |
| SCHEMBL11085896 | 0.76 | NQO1 (0.54) | PRKDCSMN1; SMN2MAPTCYP19A1CYP1B1 | |
| SCHEMBL3427191 | 0.76 | PRKDC (0.49) | PRKDCSMN1; SMN2MAPTCYP19A1FTO | |
| SCHEMBL11084153 | 0.74 | SLC9A1 (0.47) | PRKDCSMN1; SMN2MAPTFTOCYP1B1 | |
| SCHEMBL9179291 | 0.73 | PLA2G2A (0.49) | PRKDCSMN1; SMN2CYP19A1CYP1B1MEN1 | |
| SCHEMBL9204834 | 0.73 | PRKDC (0.46) | PRKDCSMN1; SMN2MAPTCYP19A1CYP1B1 | |
| SCHEMBL6172775 | 0.72 | SMN1; SMN2 (0.54) | PRKDCSMN1; SMN2MAPTCYP19A1FTO | |
| SCHEMBL14449832 | 0.72 | PRKDC (0.45) | PRKDCSMN1; SMN2MAPTCYP19A1FTO | |
| SCHEMBL11085347 | 0.72 | PRKDC (0.45) | PRKDCSMN1; SMN2MAPTCYP19A1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729465-B1 | PYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE DAVIS & CO (US) | 2003-01-22 | — | — | EP | disclosed |