Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084174 | 1.00 | POLB (0.35) | POLBCCR2L3MBTL1TSHRALOX15 | |
| SCHEMBL11084177 | 1.00 | POLB (0.35) | POLBCCR2L3MBTL1TSHRALOX15 | |
| SCHEMBL11402075 | 0.88 | L3MBTL1 (0.43) | POLBCCR2L3MBTL1CHRM2CHRM1 | |
| SCHEMBL11402077 | 0.88 | L3MBTL1 (0.43) | POLBCCR2L3MBTL1CHRM2CHRM1 | |
| SCHEMBL27891475 | 0.86 | CCR2 (0.46) | CCR2L3MBTL1 | |
| SCHEMBL10596445 | 0.84 | MAP4K1 (0.30) | MAP4K1 | |
| SCHEMBL17717378 | 0.83 | ALDH1A1 (0.33) | CCR2L3MBTL1TSHRALOX15MAP4K1 | |
| SCHEMBL18720636 | 0.83 | ALDH1A1 (0.33) | CCR2L3MBTL1TSHRALOX15MAP4K1 | |
| SCHEMBL1426470 | 0.83 | L3MBTL1 (0.34) | CCR2L3MBTL1TSHRMAP4K1 | |
| SCHEMBL28830362 | 0.82 | L3MBTL1 (0.33) | CCR2L3MBTL1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461906-A | IMPROVING INTELLECTUAL CAPACITY | HOFFMANN-LA ROCHE INC. (US) | 1984-07-24 | — | — | US | disclosed |
| EP-0024030-B1 | PYRROLIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-03-30 | — | — | EP | disclosed |
| EP-0024030-A1 | Pyrrolidine derivatives, processes for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-02-18 | — | — | EP | disclosed |
| US-4248865-A | BROAD-SPECTRUM ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1981-02-03 | — | — | US | disclosed |
| EP-0009670-A1 | Aminoglycoside derivatives, process for their preparation and pharmaceutical compositions | SHIONOGI & CO., LTD. (JP) | 1980-04-16 | — | — | EP | disclosed |