SCHEMBL1108450

SCHEMBL1108450

Cc1cc(C(=O)CC=O)cc(C)c1O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.51
MEN1 O00255 4/20 0.51
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
ESR1 P03372 3/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2B6 P20813 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TTR P02766 1/20 0.37
ESR2 Q92731 1/20 0.36
HMGB1 P09429 1/20 0.35
CXCL12 P48061 1/20 0.35
EEF2K O00418 1/20 0.35
SRC P12931 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038309 0.79 KMT2A (0.53) KMT2AMEN1NPC1ALDH1A1MAPT
SCHEMBL11396203 0.78 MEN1 (0.51) KMT2AMEN1NPC1ALDH1A1MAPT
SCHEMBL6812056 0.77 KMT2A (0.51) KMT2AMEN1NPC1ALDH1A1MAPT
SCHEMBL16233180 0.77 KMT2A (0.51) KMT2AMEN1NPC1ALDH1A1MAPT
SCHEMBL13903317 0.76 MEN1 (0.30) KMT2AMEN1NPC1
SCHEMBL13984335 0.76 ALOX5 (0.53) KMT2AMEN1ALDH1A1MAPTCYP1A2
SCHEMBL31456599 0.76 PKM (0.56) KMT2AMEN1ALDH1A1MAPTCYP1A2
SCHEMBL9862861 0.75 GSK3B (0.52) KMT2AMEN1NPC1ALDH1A1MAPT
SCHEMBL8038602 0.75 KMT2A (0.50) KMT2AMEN1NPC1ALDH1A1MAPT
SCHEMBL8461664 0.73 ALDH1A1 (0.50) KMT2AMEN1NPC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8198222-B2 Tartaric acid derivatives as fuel economy improvers and antiwear agents in crankcase oils and preparations thereof THE LUBRIZOL CORPORATION (US) 2012-06-12 US disclosed
US-8153565-B2 Lubricant composition for a final drive axle THE LUBRIZOL CORPORATION (US) 2012-04-10 US disclosed
US-20100286007-A1 Tartaric Acid Derivatives as Fuel Economy Improvers and Antiwear Agents in Crankcase Oils and Preparation Thereof THE LUBRIZOL CORPORATION (US) 2010-11-11 US disclosed
US-7807611-B2 Tartaric acid derivatives as fuel economy improvers and antiwear agents in crankcase oils and preparation thereof THE LUBRIZOL CORPORATION (US) 2010-10-05 US disclosed
US-20100227784-A1 Tartaric Acid Derivatives as Fuel Economy Improvers and Antiwear Agents in Crankcase Oils and Preparations Thereof Th Lubrizol Corporation (US) 2010-09-09 US disclosed
US-7772169-B2 Low ash stationary gas engine lubricant THE LUBRIZOL CORPORATION (US) 2010-08-10 US disclosed
US-20100173812-A1 Tartaric Acid Derivatives as Fuel Economy Improvers and Antiwear Agents in Crankcase Oils and Preparations Thereof THE LUBRIZOL CORPORATION (US) 2010-07-08 US disclosed
US-7651987-B2 Tartaric acid derivatives as fuel economy improvers and antiwear agents in crankcase oils and preparation thereof THE LUBRIZOL CORPORATION (US) 2010-01-26 US disclosed
US-7648949-B2 Low phosphorus cobalt complex-containing engine oil lubricant THE LUBRIZOL CORPORATION (US) 2010-01-19 US disclosed
US-20090298727-A1 Lubricant Composition for a Final Drive Axle THE LUBRIZOL CORPORATION (US) 2009-12-03 US disclosed
US-20090064956-A1 Ashless Consumable Engine Oil THE LUBRIZOL CORPORATION (US) 2009-03-12 US disclosed