Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086602 | 0.84 | ALDH1A1 (0.41) | MAPTGAAKMT2AALDH1A1MAPK1 | |
| SCHEMBL11084724 | 0.83 | ALDH1A1 (0.45) | MAPTNPC1LMNAGAAKMT2A | |
| SCHEMBL11084270 | 0.83 | MEN1 (0.37) | MAPTKDM4ENPC1LMNAP4HTM | |
| SCHEMBL11080774 | 0.81 | NPC1 (0.42) | MAPTKDM4ENPC1LMNAGAA | |
| SCHEMBL11084914 | 0.81 | KDR (0.46) | MAPTNPC1LMNAP4HTMGAA | |
| SCHEMBL11083402 | 0.78 | CSNK2A1 (0.42) | MAPTNPC1LMNAGAAKMT2A | |
| SCHEMBL11092605 | 0.73 | L3MBTL1 (0.43) | KDM4ENPC1LMNAGAAKMT2A | |
| SCHEMBL4543435 | 0.67 | GPR35 (0.41) | MAPTKDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL10406124 | 0.67 | KMT2A (0.41) | MAPTKDM4ELMNAKMT2AMEN1 | |
| SCHEMBL30827844 | 0.67 | PIP4K2C (0.64) | MAPTALDH1A1HTTAURKAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126970-A2 | Anxiolytic and anti-depressant thienopyridine derivatives | BEECHAM GROUP PLC (GB) | 1984-12-05 | — | — | EP | claimed |
| EP-0126970-A2 | Anxiolytic and anti-depressant thienopyridine derivatives | BEECHAM GROUP PLC (GB) | 1984-12-05 | — | — | EP | disclosed |