Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.66 |
| ▸ | FEN1 | P39748 | 1/20 | 0.66 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352723 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL14825074 | 0.86 | ALDH1A1 (0.76) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL28269605 | 0.86 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL4036255 | 0.84 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL4942886 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL11634779 | 0.81 | ERCC5 (0.68) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL10028045 | 0.80 | RAB9A (0.69) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL21067946 | 0.80 | RAB9A (0.69) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL11085446 | 0.80 | MEN1 (0.67) | ALDH1A1MEN1KMT2ANPSR1RAB9A | |
| SCHEMBL12670456 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052365-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-03-09 | — | — | US | claimed |
| JP-2006505526-A | — | — | 2006-02-16 | — | — | JP | claimed |
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | claimed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| CN-116535371-A | Guanidine-containing phenyl furan carboxamide compound and application thereof | 华南农业大学 | 2023-08-04 | — | — | CN | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-110294749-B | (S) -1, 3-thiazole phenyl furan thiocarbamate compound and preparation method and application thereof | 华南农业大学 | 2022-01-25 | — | — | CN | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| CN-110183428-B | Furan thiocarbamate compound containing 1,2,3, 4-tetrazole and preparation method and application thereof | 华南农业大学 | 2021-08-03 | — | — | CN | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| US-7939554-B2 | Of Src homology protein tyrosine phosphatase 1; phenyl isothiazolones or a benzo-1,4-quinone; antineoplastic agents; immunostimulants inducing a cytokine response; side effect reduction | THE CLEVELAND CLINIC FOUNDATION (US) | 2011-05-10 | — | — | US | disclosed |
| WO-2010065881-A2 | METHODS OF TREATING AN OVERWEIGHT OR OBESE SUBJECT | ZAFGEN CORPORATION (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |
| US-20080103160-A1 | Protein phosphatase inhibitors | THE CLEVELAND CLINIC FOUNDATION | 2008-05-01 | — | — | US | disclosed |
| US-20060052365-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2006-03-09 | — | — | US | disclosed |
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052365-A1 | Protease inhibitors | CTSS, CTSE, CMA1 | ALDH1A1 1528/4885MEN1 3726/4885KMT2A 3606/4885 |
| US-20080103160-A1 | Protein phosphatase inhibitors | PPM1A, DUSP15, PPM1B | ALDH1A1 1282/4885MEN1 3553/4885KMT2A 2203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.