Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090839 | 0.83 | FFAR1 (0.43) | FFAR1ALDH1A1KDM4EGAAKDR | |
| SCHEMBL29957028 | 0.80 | EGFR (0.50) | HPGDHSD17B10KDRMEN1NPC1 | |
| SCHEMBL27787171 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL28085556 | 0.74 | NPC1 (0.62) | ALDH1A1HPGDMEN1NPC1KMT2A | |
| SCHEMBL15530810 | 0.67 | MAPT (0.58) | ALDH1A1KDM4EHPGDGAAMEN1 | |
| SCHEMBL23426225 | 0.67 | TRIM24 (0.47) | ALDH1A1KDM4EHPGDHSD17B10MEN1 | |
| SCHEMBL3713256 | 0.67 | TRIM24 (0.47) | ALDH1A1KDM4EGAAMEN1NPC1 | |
| SCHEMBL6759306 | 0.67 | BDKRB1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10KDR | |
| SCHEMBL4725432 | 0.66 | EGFR (0.47) | ALDH1A1KDM4EHPGDHSD17B10KDR | |
| SCHEMBL11070290 | 0.66 | TBXAS1 (0.62) | FFAR1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100158-A2 | (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters | THE UPJOHN COMPANY (US) | 1984-02-08 | — | — | EP | disclosed |