Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | FABP1 | P07148 | 1/20 | 0.49 |
| ▸ | FABP6 | P51161 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787171 | 0.86 | KDM4E (0.51) | EGFRKMT2AHSD17B10KDRHPGD | |
| SCHEMBL15530810 | 0.84 | MAPT (0.58) | EGFRHIF1AUTS2RRAB9AMEN1 | |
| SCHEMBL28085556 | 0.83 | NPC1 (0.62) | EGFRHIF1ANR2F2MEN1NPC1 | |
| SCHEMBL11085488 | 0.80 | FFAR1 (0.41) | RAB9AMEN1NPC1KMT2AHSD17B10 | |
| SCHEMBL4725432 | 0.80 | EGFR (0.47) | EGFRFABP1FABP6BACE1PSMB1 | |
| SCHEMBL4780744 | 0.80 | EGFR (0.47) | EGFRFABP1FABP6BACE1HIF1A | |
| SCHEMBL27874525 | 0.79 | MEN1 (0.47) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL23426225 | 0.78 | TRIM24 (0.47) | UTS2RTRIM24TRIM33RAB9AMEN1 | |
| SCHEMBL14291447 | 0.78 | EGFR (0.45) | EGFRFABP1FABP6BACE1PSMB1 | |
| SCHEMBL22625722 | 0.77 | CASP6 (0.43) | HIF1ATRIM24TRIM33MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |