SCHEMBL11085706

SCHEMBL11085706

C=Cc1ccncc1C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.35
KIF11 P52732 3/20 0.33
NFE2L2 Q16236 1/20 0.33
LATS1 O95835 1/20 0.33
GAA P10253 2/20 0.33
IMPDH2 P12268 1/20 0.33
SLC22A12 Q96S37 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
AXL P30530 1/20 0.31
ALDH1A1 P00352 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM5A P29375 1/20 0.30
KDM4C Q9H3R0 1/20 0.30
CHUK O15111 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3663643 0.84 NFE2L2 (0.36) ERN1KIF11NFE2L2GAAIMPDH2
SCHEMBL29988644 0.83 NFE2L2 (0.40) ERN1KIF11NFE2L2LATS1GAA
SCHEMBL25403009 0.82 NFE2L2 (0.37) ERN1KIF11NFE2L2LATS1GAA
SCHEMBL9274800 0.80 ERN1 (0.48) ERN1KIF11NFE2L2LATS1GAA
SCHEMBL22380099 0.80 ALOX5 (0.36) KIF11IMPDH2ALDH1A1
SCHEMBL30800801 0.80 ERN1 (0.48) ERN1KIF11NFE2L2LATS1GAA
SCHEMBL1310289 0.77 KIF11 (0.37) KIF11LATS1GAASLC22A12NPC1
SCHEMBL20772453 0.73 KIF11 (0.41) KIF11LATS1GAASLC22A12NPC1
SCHEMBL14985274 0.73 IMPDH2 (0.42) ERN1GAAIMPDH2AXLALDH1A1
SCHEMBL12530511 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114870806-B Application of ion hybrid porous material in separation of cyclohexene and cyclohexane and preparation method thereof 浙江大学 2023-04-18 CN disclosed
CN-114870806-A Application of ion hybrid porous material in separation of cyclohexene and cyclohexane and preparation method thereof 浙江大学 2022-08-09 CN disclosed
US-4490535-A 4-(3- and 4-Chlorocyclohex-3-enyl)pyridine intermediates ETHYL CORPORATION (US) 1984-12-25 US disclosed
US-4405792-A Substituted pyridines and their preparation ETHYL CORPORATION (US) 1983-09-20 US disclosed