SCHEMBL110859

SCHEMBL110859

C1=C(Cc2ccccc2)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.52
BCL2 P10415 1/20 0.38
BCL2L1 Q07817 1/20 0.38
TSHR P16473 4/20 0.37
ALDH1A1 P00352 2/20 0.37
LTA4H P09960 1/20 0.37
TAAR1 Q96RJ0 2/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
ADRA2A P08913 1/20 0.36
CYP2D6 P10635 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
ADRA1D P25100 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36
IDO1 P14902 1/20 0.36
TP53 P04637 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.36
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28831761 0.98 CALM1 (0.50) CALM1BCL2BCL2L1TSHRALDH1A1
Hydrochloric Acid SCHEMBL28817569 0.98 CALM1 (0.50) CALM1BCL2BCL2L1TSHRALDH1A1
SCHEMBL27931008 0.98 CALM1 (0.50) CALM1BCL2BCL2L1TSHRALDH1A1
SCHEMBL2585502 0.85 CALM1 (0.42) CALM1BCL2BCL2L1ALDH1A1LTA4H
SCHEMBL2333440 0.84 CALM1 (0.46) CALM1BCL2BCL2L1ALDH1A1LMNA
Acrylic Acid SCHEMBL28891256 0.83 ALDH1A1 (0.37) CALM1ALDH1A1LMNACYP3A4
SCHEMBL1399903 0.82 ALDH1A1 (0.50) CALM1ALDH1A1LMNAKDM4EMAPT
SCHEMBL3707221 0.82 CALM1 (0.39) CALM1ALDH1A1IDH1DAO
SCHEMBL21305456 0.82 CALM1 (0.39) CALM1TSHRALDH1A1LTA4HTAAR1
SCHEMBL111084 0.81 ALDH1A1 (0.49) CALM1ALDH1A1LMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2978 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731716-A1 COATING COMPOSITIONS DuPont Toray Specialty Materials Kabushiki Kaisha (JP) 2026-04-29 EP claimed
EP-4476578-B1 INTERFEROMETER FOR A PHOTONIC INTEGRATED CIRCUIT SMART PHOTONICS HOLDING B V (NL) 2026-03-04 EP claimed
US-20250364384-A1 REDUCTION OF CRACKS IN REDISTRIBUTION STRUCTURE TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2025-11-27 US claimed
US-12476178-B2 Reduction of cracks in redistribution structure TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2025-11-18 US claimed
EP-4327373-B1 MULTILAYER SUPERCONDUCTING STRUCTURES FOR CRYOGENIC ELECTRONICS MICROSOFT TECHNOLOGY LICENSING LLC (US) 2025-11-12 EP claimed
US-12424574-B2 Polymer coated semiconductor devices and hybrid bonding to form semiconductor assemblies MICRON TECHNOLOGY, INC. (US) 2025-09-23 US claimed
EP-4025957-B1 AN ELECTRO-OPTIC MODULATOR LIGENTEC SA (CH) 2025-05-07 EP claimed
EP-4066029-B1 WAVEGUIDE STRUCTURE FOR A PHOTONIC INTEGRATED CIRCUIT SMART PHOTONICS HOLDING B V (NL) 2025-02-19 EP claimed
WO-2025028465-A1 COATING COMPOSITIONS DUPONT TORAY SPECIALTY MATERIALS KABUSHIKI KAISHA (JP) 2025-02-06 WO claimed
US-12210040-B2 Systems and methods for integrated shielding in a current sensor ALLEGRO MICROSYSTEMS, LLC (US) 2025-01-28 US claimed
US-5189045-A Antiserotonine agent ADIR ET COMPAGNIE (FR) 1993-02-23 US claimed
EP-0313077-B1 PREPARATION OF CYCLOBUTARENES VIA THE STEAM PYROLYSIS OF AROMATIC DERIVATIVES THE DOW CHEMICAL COMPANY (US) 1992-07-08 EP claimed
EP-0213080-B1 HYDROGENATED PYRIDINE DERIVATIVES CIBA-GEIGY AG (CH) 1992-05-20 EP claimed
US-5068396-A Arylcyclobutene carboxylate esters SHELL OIL COMPANY (US) 1991-11-26 US claimed
EP-0453785-A1 Method of making multilayer thin film circuit comprising integrated thin film resistors Oerlikon Contraves AG (CH) 1991-10-30 EP claimed
EP-0428437-A1 1,2-Benzisoxazole derivatives, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1991-05-22 EP claimed
US-4939160-A Nootropic agents CIBA-GEIGY CORPORATION (US) 1990-07-03 US claimed
US-4833169-A MEMORY ACTIVATORS CIBA-GEIGY CORPORATION (US) 1989-05-23 US claimed
US-4704388-A ANTIULCER, CYTOPROTECTIVE RORER PHARMACEUTICAL CORPORATION (US) 1987-11-03 US claimed
US-4595683-A Gastrointestinal disorders, antiulcer agents WILLIAM H. RORER, INC. (US) 1986-06-17 US claimed