SCHEMBL28831761

SCHEMBL28831761

C1=C(Cc2ccccc2)CC1.[PbH2]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.50
BCL2 P10415 1/20 0.37
BCL2L1 Q07817 1/20 0.37
TSHR P16473 4/20 0.36
ALDH1A1 P00352 2/20 0.36
LTA4H P09960 1/20 0.35
TAAR1 Q96RJ0 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2D6 P10635 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
IDO1 P14902 1/20 0.35
TP53 P04637 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110859 0.98 CALM1 (0.52) CALM1BCL2BCL2L1TSHRALDH1A1
Hydrochloric Acid SCHEMBL28817569 0.95 CALM1 (0.50) CALM1BCL2BCL2L1TSHRALDH1A1
SCHEMBL27931008 0.95 CALM1 (0.50) CALM1BCL2BCL2L1TSHRALDH1A1
SCHEMBL2585502 0.83 CALM1 (0.42) CALM1BCL2BCL2L1ALDH1A1LTA4H
SCHEMBL2333440 0.82 CALM1 (0.46) CALM1BCL2BCL2L1ALDH1A1LMNA
SCHEMBL28561920 0.81 ALDH1A1 (0.48) CALM1ALDH1A1LMNAKDM4EMAPT
Acrylic Acid SCHEMBL28891256 0.81 ALDH1A1 (0.37) CALM1ALDH1A1LMNACYP3A4
SCHEMBL1399903 0.80 ALDH1A1 (0.50) CALM1ALDH1A1LMNAKDM4EMAPT
SCHEMBL21305456 0.80 CALM1 (0.39) CALM1TSHRALDH1A1LTA4HTAAR1
SCHEMBL3707221 0.80 CALM1 (0.39) CALM1ALDH1A1IDH1DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106104849-A Ionic conduction composite diaphragm 国际商业机器公司 2016-11-09 CN claimed