Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645709 | 0.82 | DRD4 (0.44) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL11079217 | 0.80 | RAB9A (0.50) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL11085316 | 0.80 | KCNH2 (0.50) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL942231 | 0.80 | ALDH1A1 (0.47) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL944187 | 0.77 | ALDH1A1 (0.57) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL1645707 | 0.75 | TDP1 (0.50) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL2231028 | 0.75 | NOS2 (0.55) | NOS1NOS2NOS3 | |
| SCHEMBL10504713 | 0.75 | SMN1; SMN2 (0.52) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL1645711 | 0.74 | KCNH2 (0.42) | KCNH2SMN1; SMN2ALDH1A1MAPTKMT2A | |
| SCHEMBL11082778 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1MAPTTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443246-A | Herbicidal pyridyl-ethoxy-phenyl urea derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0067718-A1 | Urea derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-12-22 | — | — | EP | disclosed |