Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15173980 | 0.85 | KCNH2 (0.50) | NPC1SMN1; SMN2KCNH2HDAC1HDAC8 | |
| SCHEMBL8202749 | 0.82 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2KCNH2LMNA | |
| SCHEMBL8196269 | 0.81 | SMN1; SMN2 (0.48) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL11086008 | 0.80 | KCNH2 (0.56) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL11087448 | 0.79 | LMNA (0.59) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL7752804 | 0.76 | NOS2 (0.42) | ALDH1A1KMT2ASMN1; SMN2KCNH2HDAC1 | |
| SCHEMBL8209407 | 0.76 | FFAR1 (0.49) | GRM5 | |
| SCHEMBL3021299 | 0.76 | RAB9A (0.59) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL9977688 | 0.74 | SMN1; SMN2 (0.42) | ALDH1A1KMT2ASMN1; SMN2KCNH2TSHR | |
| SCHEMBL6501447 | 0.74 | SMN1; SMN2 (0.65) | RAB9ANPC1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443246-A | Herbicidal pyridyl-ethoxy-phenyl urea derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0067718-A1 | Urea derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-12-22 | — | — | EP | disclosed |