Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16921623 | 0.82 | PDE3B (0.33) | MEN1KMT2A | |
| SCHEMBL10878446 | 0.60 | L3MBTL1 (0.47) | L3MBTL1CYP1A2KDM4E | |
| SCHEMBL16921622 | 0.53 | PTGS2 (0.30) | — | |
| SCHEMBL18633341 | 0.53 | CYP19A1 (0.33) | KMT2A | |
| SCHEMBL12327913 | 0.51 | — | — | |
| SCHEMBL22606534 | 0.51 | PKM (0.31) | — | |
| SCHEMBL239276 | 0.51 | CA9 (0.36) | MEN1CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL14071570 | 0.51 | POLB (0.38) | CYP1A2TSHRKDM4E | |
| SCHEMBL14071572 | 0.49 | CA9 (0.35) | MEN1CYP3A4KMT2AKDM4ETP53 | |
| SCHEMBL8213378 | 0.48 | ALDH1A1 (0.44) | CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033083-B1 | N,N-DIALKYL -0-(PYRAZOL-5-YL)CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |
| US-4447444-A | 1-Alkyl-3-alkoxymethyl-4-alkoxy-5-dialkylcarbamoyloxy pyrazoles and use as aphicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-08 | — | — | US | disclosed |
| EP-0033083-A2 | N,N-dialkyl -0-(pyrazol-5-yl)carbamates, process for their preparation and their use as insecticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-05 | — | — | EP | disclosed |