Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | ACE | P12821 | 6/20 | 0.43 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086488 | 1.00 | CA2 (0.44) | CA2ACERENKDM4EF2 | |
| SCHEMBL11084537 | 0.84 | CA2 (0.44) | CA2ACERENKDM4EF2 | |
| SCHEMBL11084531 | 0.84 | CA2 (0.44) | CA2ACERENKDM4EF2 | |
| SCHEMBL11090981 | 0.78 | ACE (0.43) | CA2ACERENKDM4EF2 | |
| SCHEMBL11090985 | 0.78 | ACE (0.43) | CA2ACERENKDM4EF2 | |
| SCHEMBL11050059 | 0.75 | ACE (0.52) | ACELMNA | |
| SCHEMBL11228795 | 0.75 | MAPT (0.47) | CA2ACERENKDM4EF2 | |
| SCHEMBL11122413 | 0.75 | CA2 (0.62) | CA2ACEKDM4ELMNAMAPT | |
| SCHEMBL19387581 | 0.73 | ACE (0.62) | ACERENKDM4EF2LMNA | |
| SCHEMBL19387587 | 0.73 | ACE (0.62) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450275-A | HYPOTENSIVE AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1984-05-22 | — | — | US | disclosed |