Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23067450 | 0.89 | HSD17B10 (0.67) | PARP1HPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL11091860 | 0.85 | NPC1 (0.63) | PARP1HPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL28406248 | 0.82 | PARP1 (0.59) | PARP1HPGDHSD17B10ALDH1A1MAPT | |
| SCHEMBL5851806 | 0.80 | SLC6A7 (0.66) | PARP1HPGDMGLLALDH1A1MAPT | |
| SCHEMBL11085975 | 0.80 | ALDH1A1 (0.74) | PARP1MGLLALDH1A1LMNAHTT | |
| SCHEMBL15566861 | 0.79 | LRRK2 (0.54) | HPGDALDH1A1MAPTLMNA | |
| SCHEMBL243754 | 0.78 | MRGPRX4 (0.73) | HPGDHSD17B10MAPTHTTSMN1; SMN2 | |
| SCHEMBL11088706 | 0.78 | PARP1 (0.66) | PARP1LMNASMN1; SMN2SIGMAR1 | |
| SCHEMBL27964892 | 0.78 | SIGMAR1 (0.63) | HPGDMGLLALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL9647665 | 0.77 | MRGPRX4 (0.71) | HPGDHSD17B10MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426382-A | HYPOTENSIVE AGENTS | SANKYO COMPANY LIMITED (JP) | 1984-01-17 | — | — | US | disclosed |