Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15173980 | 0.79 | KCNH2 (0.50) | KCNH2NPC1SMN1; SMN2 | |
| SCHEMBL6793846 | 0.79 | KMT2A (0.62) | LMNAKCNH2MEN1KMT2AMAPT | |
| SCHEMBL11079217 | 0.79 | RAB9A (0.50) | LMNAKCNH2KMT2AMAPTRAB9A | |
| SCHEMBL8196269 | 0.78 | SMN1; SMN2 (0.48) | LMNAKCNH2MEN1KMT2AMAPT | |
| SCHEMBL6489114 | 0.77 | SMN1; SMN2 (0.51) | LMNAKCNH2MEN1KMT2AMAPT | |
| SCHEMBL6492317 | 0.77 | LMNA (0.51) | LMNAKCNH2MEN1KMT2AMAPT | |
| SCHEMBL10504130 | 0.77 | MEN1 (0.50) | LMNAKCNH2MEN1KMT2AMAPT | |
| SCHEMBL8202749 | 0.76 | ALDH1A1 (0.47) | LMNAKCNH2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL942234 | 0.76 | HTT (0.59) | LMNAKCNH2MEN1KMT2AMAPT | |
| SCHEMBL6487610 | 0.75 | MAPT (0.48) | LMNAKCNH2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443246-A | Herbicidal pyridyl-ethoxy-phenyl urea derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| EP-0067718-A1 | Urea derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-12-22 | — | — | EP | disclosed |