Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | MERTK | Q12866 | 16/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 14/20 | 0.48 |
| ▸ | GAS6 | Q14393 | 12/20 | 0.48 |
| ▸ | FLT3 | P36888 | 9/20 | 0.48 |
| ▸ | AXL | P30530 | 4/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081631 | 0.96 | HCAR3 (0.48) | MAPK8KDM6BKDM4CMERTKTYRO3 | |
| SCHEMBL11081740 | 0.94 | HCAR3 (0.47) | MAPK8KDM6BKDM4CMERTKTYRO3 | |
| SCHEMBL11082898 | 0.94 | HCAR3 (0.47) | MAPK8KDM6BKDM4CMERTKTYRO3 | |
| SCHEMBL11083328 | 0.91 | KDM6B (0.47) | MAPK8KDM6BKDM4CMERTKTYRO3 | |
| SCHEMBL25268627 | 0.85 | MAPK8 (0.51) | MAPK8KDM6BKDM4CMERTKTYRO3 | |
| SCHEMBL11083556 | 0.85 | MERTK (0.47) | MAPK8MERTKTYRO3GAS6FLT3 | |
| SCHEMBL11083131 | 0.83 | RAB9A (0.51) | MERTKTYRO3GAS6FLT3AXL | |
| SCHEMBL11086984 | 0.82 | PKM (0.36) | MAPK8KDM6BKDM4CMERTKTYRO3 | |
| SCHEMBL11091563 | 0.81 | HCAR3 (0.48) | MERTKTYRO3GAS6HCAR3 | |
| SCHEMBL11087833 | 0.81 | ASPH (0.55) | KDM6BKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447422-A | Penicillins and compositions containing them | BEECHAM GROUP P.1.C. (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0067610-A1 | Penicillins, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |