Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.65 |
| ▸ | GCGR | P47871 | 2/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | RAF1 | P04049 | 3/20 | 0.63 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081371 | 0.88 | MAPK14 (0.70) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL11082212 | 0.85 | MAPK13 (0.87) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL6468983 | 0.84 | MAPT (0.63) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL11081583 | 0.84 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL30713384 | 0.84 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL1132001 | 0.83 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL8104080 | 0.83 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL1308320 | 0.83 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL15400046 | 0.83 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL15400824 | 0.83 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005219-B1 | ARYLIMIDAZOLES, THEIR SYNTHESIS AND PHARMACEUTICAL OR VETERINARY PREPARATIONS CONTAINING THEM | A/S Dumex (Dumex Ltd.) (DK) | 1981-07-22 | — | — | EP | claimed |
| EP-0005219-A1 | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them | A/S Dumex (Dumex Ltd.) (DK) | 1979-11-14 | — | — | EP | claimed |
| US-4424229-A | ANALGESICS | A/S DUMEX (DUMEX LTD.) (DK) | 1984-01-03 | — | — | US | disclosed |
| EP-0005219-B1 | ARYLIMIDAZOLES, THEIR SYNTHESIS AND PHARMACEUTICAL OR VETERINARY PREPARATIONS CONTAINING THEM | A/S Dumex (Dumex Ltd.) (DK) | 1981-07-22 | — | — | EP | disclosed |
| EP-0005219-A1 | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them | A/S Dumex (Dumex Ltd.) (DK) | 1979-11-14 | — | — | EP | disclosed |