Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 12/20 | 0.87 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.87 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.87 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.87 |
| ▸ | GCGR | P47871 | 11/20 | 0.87 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.87 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | RAF1 | P04049 | 2/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.66 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.66 |
| ▸ | FRK | P42685 | 2/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.66 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.66 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.66 |
| ▸ | GSK3B | P49841 | 2/20 | 0.66 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.66 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.66 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648503 | 0.93 | MAPK11 (1.00) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL8008805 | 0.92 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL15400824 | 0.92 | NOX1 (0.85) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL5698677 | 0.89 | ALOX5 (0.74) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL11081371 | 0.88 | MAPK14 (0.70) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL3455232 | 0.87 | NOX1 (0.77) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL8104080 | 0.86 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL15400046 | 0.86 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL1308320 | 0.86 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL1132001 | 0.86 | MAPK13 (0.86) | MAPK13MAPK12MAPK11MAPK14GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005219-B1 | ARYLIMIDAZOLES, THEIR SYNTHESIS AND PHARMACEUTICAL OR VETERINARY PREPARATIONS CONTAINING THEM | A/S Dumex (Dumex Ltd.) (DK) | 1981-07-22 | — | — | EP | claimed |
| EP-0005219-A1 | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them | A/S Dumex (Dumex Ltd.) (DK) | 1979-11-14 | — | — | EP | claimed |
| US-4424229-A | ANALGESICS | A/S DUMEX (DUMEX LTD.) (DK) | 1984-01-03 | — | — | US | disclosed |
| US-4322428-A | 2(4-Fluorophenyl)-4,5,-bis(4-methoxyphenyl)thiazole and method of use | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0037274-A1 | Substituted triaryl thiazole compounds | ELI LILLY AND COMPANY (US) | 1981-10-07 | — | — | EP | disclosed |
| EP-0005219-B1 | ARYLIMIDAZOLES, THEIR SYNTHESIS AND PHARMACEUTICAL OR VETERINARY PREPARATIONS CONTAINING THEM | A/S Dumex (Dumex Ltd.) (DK) | 1981-07-22 | — | — | EP | disclosed |
| EP-0005219-A1 | Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them | A/S Dumex (Dumex Ltd.) (DK) | 1979-11-14 | — | — | EP | disclosed |