Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091135 | 0.91 | CXCL8 (0.41) | CXCL8SLC6A3ALDH1A1MAPTNPSR1 | |
| SCHEMBL11097033 | 0.88 | CHRM1 (0.54) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL11089498 | 0.87 | TBXAS1 (0.45) | ALDH1A1MAPTPKMNLRP3TBXAS1 | |
| SCHEMBL11092614 | 0.85 | CXCL8 (0.51) | CXCL8ALDH1A1PKMNLRP3KDM4E | |
| SCHEMBL11092566 | 0.84 | TSHR (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL11087036 | 0.84 | HTR2A (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL11094079 | 0.83 | CYP3A4 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL11085687 | 0.82 | DHFR (0.38) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL11090453 | 0.82 | CXCL8 (0.49) | CXCL8SLC6A2SLC6A4SLC6A3CAMK2A | |
| SCHEMBL11084311 | 0.82 | CXCL8 (0.75) | CXCL8SLC6A2SLC6A4SLC6A3CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58197676-A | — | — | None | — | — | JP | disclosed |
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| JP-S58197676-A | CELL | MATSUSHITA ELECTRIC IND CO LTD | 1983-11-17 | — | — | JP | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |