Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087906 | 0.88 | CXCL8 (0.51) | CHRM1SLC6A2SLC6A4SLC6A3CYP2C9 | |
| SCHEMBL11084291 | 0.85 | SLC6A4 (0.47) | SLC6A2SLC6A4SLC6A3CYP2C9L3MBTL1 | |
| SCHEMBL11087036 | 0.84 | HTR2A (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL11091135 | 0.84 | CXCL8 (0.41) | SLC6A3CYP2C9GAAALDH1A1L3MBTL1 | |
| SCHEMBL11089474 | 0.84 | CHRM1 (0.76) | CHRM1SLC6A2SLC6A4SLC6A3CYP2C9 | |
| SCHEMBL11085687 | 0.83 | DHFR (0.38) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL11093624 | 0.82 | CHRM1 (0.50) | CHRM1SLC6A2SLC6A4SLC6A3MRGPRX4 | |
| SCHEMBL11094498 | 0.82 | CHRM1 (0.57) | CHRM1SLC6A2SLC6A4SLC6A3CYP2C9 | |
| SCHEMBL11094079 | 0.81 | CYP3A4 (0.50) | SLC6A2SLC6A4SLC6A3ALDH1A1KCNH2 | |
| SCHEMBL11089498 | 0.80 | TBXAS1 (0.45) | ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |