Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093373 | 0.85 | GRIA2 (0.43) | ALDH1A1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL11093428 | 0.85 | CA12 (0.45) | L3MBTL1ALDH1A1POLBUSP2KDM4E | |
| SCHEMBL11094596 | 0.82 | HSD11B1 (0.41) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL11092352 | 0.78 | HTT (0.41) | L3MBTL1ALDH1A1POLBUSP2NPSR1 | |
| SCHEMBL11092543 | 0.75 | MAPT (0.44) | ALDH1A1POLBUSP2KDM4ENPSR1 | |
| SCHEMBL11090372 | 0.74 | HCRTR1 (0.44) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11091505 | 0.74 | POLB (0.39) | POLBTDP1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL11095201 | 0.71 | MAPT (0.49) | ALDH1A1POLBTDP1MEN1KMT2A | |
| SCHEMBL11091893 | 0.69 | ALDH1A1 (0.43) | ALDH1A1CYP3A4POLBKDM4EMEN1 | |
| SCHEMBL11787227 | 0.67 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1POLBTDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055917-B1 | NEW BENZOTHIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |
| US-4397849-A | AUTOIMMUNE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-09 | — | — | US | disclosed |
| EP-0055917-A1 | New benzothiazine derivatives, processes for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-14 | — | — | EP | disclosed |