Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086745 | 0.94 | ALOX15 (0.45) | ALOX15LMNATSHRSMN1; SMN2RAB9A | |
| SCHEMBL11090694 | 0.92 | ALOX15 (0.41) | ALOX15LMNATSHRSMN1; SMN2RAB9A | |
| SCHEMBL11094276 | 0.86 | CYP3A4 (0.62) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11091589 | 0.83 | LMNA (0.41) | ALOX15LMNATSHRSMN1; SMN2RAB9A | |
| SCHEMBL11083004 | 0.82 | CYP1A2 (0.55) | ALOX15LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL11091615 | 0.81 | CYP3A4 (0.62) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11090434 | 0.79 | CYP3A4 (0.59) | ALOX15CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15501165 | 0.76 | CALM1 (0.39) | SMN1; SMN2TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11087697 | 0.73 | CYP3A4 (0.69) | ALOX15SMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11084093 | 0.73 | HPGD (0.42) | LMNASMN1; SMN2RAB9ATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482728-A | ANTIFERTILITY AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1984-11-13 | — | — | US | disclosed |
| US-4357344-A | Polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes in insect population control | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-11-02 | — | — | US | disclosed |
| US-4342777-A | GROWTH INHIBITOR FOR MOSQUITO LARVAE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-08-03 | — | — | US | disclosed |