Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928680 | 0.74 | KDM4E (0.37) | PARP1KDM4EMEN1TDP2ALDH1A1 | |
| SCHEMBL8948488 | 0.72 | PARP1 (0.38) | PARP1MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11381582 | 0.72 | ALDH1A1 (0.44) | IDO1KDM4EMEN1CES2GMNN | |
| SCHEMBL11159842 | 0.72 | RAB9A (0.40) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL11155587 | 0.69 | DDB1 (0.37) | IDO1KDM4EMEN1CES2GMNN | |
| SCHEMBL8948740 | 0.68 | CA1 (0.49) | ALDH1A1TP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11387596 | 0.67 | NSD2 (0.41) | KDM4EMEN1ALDH1A1LMNAGLA | |
| SCHEMBL11387475 | 0.67 | MEN1 (0.50) | MEN1ALDH1A1LMNAMAPTTHRB | |
| SCHEMBL11158055 | 0.67 | MAPT (0.45) | KDM4EMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL11154239 | 0.64 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0039091-B1 | SPIROBENZOFURANONE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 1984-05-30 | — | — | EP | claimed |