Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | TOP1 | P11387 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097003 | 0.83 | HDAC6 (0.51) | HDAC6TOP1MAPTSNCACA12 | |
| SCHEMBL20116196 | 0.83 | CA1 (0.59) | HDAC6TOP1MAPTSNCACA12 | |
| SCHEMBL18083916 | 0.80 | HDAC6 (0.60) | HDAC6TOP1MAPTSNCACA12 | |
| SCHEMBL11356407 | 0.78 | HPGD (0.62) | HDAC6MAPTKDM4EPOLB | |
| SCHEMBL10029414 | 0.77 | L3MBTL1 (0.58) | HDAC6TOP1CA12CA1CA2 | |
| SCHEMBL4480718 | 0.77 | HDAC6 (0.51) | HDAC6TOP1MAPTSNCACA12 | |
| SCHEMBL24440484 | 0.77 | HDAC6 (0.60) | HDAC6TOP1MAPTCA12CA1 | |
| SCHEMBL29633482 | 0.77 | HDAC6 (0.60) | HDAC6TOP1MAPTCA12CA1 | |
| SCHEMBL31474545 | 0.77 | EPHX2 (0.50) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL10451394 | 0.77 | LMNA (0.58) | HDAC6MAPTNAMPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190106673-A1 | BIOINK COMPOSITIONS AND METHODS OF PREPARING AND USING THE SAME | UNITED STATES GOVERNMENT | 2019-04-11 | — | — | US | disclosed |
| EP-0045523-B1 | ALPHA-SUBSTITUTED UREIDOBENZYLPENICILLANIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-12-05 | — | — | EP | disclosed |
| EP-0045523-A1 | Alpha-substituted ureidobenzylpenicillanic acid derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-10 | — | — | EP | disclosed |