Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082562 | 0.89 | HTT (0.39) | — | |
| SCHEMBL26135140 | 0.85 | RAB9A (0.39) | HRH1 | |
| SCHEMBL16845861 | 0.85 | KCNH2 (0.44) | MEN1KMT2AHTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL16827934 | 0.84 | KCNH2 (0.43) | MEN1KMT2AHTR2CHTR1ASLC6A2 | |
| SCHEMBL13117192 | 0.75 | ICMT (0.46) | SIGMAR1SLC18A3GABRA1GABRB2HRH1 | |
| SCHEMBL21082452 | 0.72 | LGALS3 (0.35) | — | |
| SCHEMBL25835836 | 0.72 | EP300 (0.40) | KMT2A | |
| SCHEMBL2859000 | 0.72 | HTT (0.44) | SIGMAR1SLC18A3MEN1KMT2AKHK | |
| SCHEMBL28079922 | 0.72 | SIGMAR1 (0.44) | SIGMAR1SLC18A3GABRA1GABRB2HTR3E | |
| SCHEMBL239491 | 0.71 | MEN1 (0.46) | SIGMAR1SLC18A3MEN1KMT2AGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481360-A | 4H-1,2,4-Triazol-3-yl compounds | THE UPJOHN COMPANY (US) | 1984-11-06 | — | — | US | disclosed |