Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094863 | 0.90 | HPGD (0.47) | DRD4DRD2DRD3HPGDPOLB | |
| SCHEMBL11093546 | 0.88 | DRD2 (0.60) | DRD4DRD2DRD3HPGD | |
| SCHEMBL11092131 | 0.87 | DRD4 (0.51) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL11096893 | 0.86 | SMN1; SMN2 (0.58) | POLBALDH1A1MEN1KMT2A | |
| SCHEMBL11096795 | 0.85 | NPC1 (0.48) | DRD2HPGDPOLBALDH1A1MEN1 | |
| SCHEMBL11096164 | 0.79 | CXCR6 (0.48) | DRD4DRD2DRD3 | |
| SCHEMBL11270191 | 0.79 | CXCR4 (0.47) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL11092436 | 0.79 | MEN1 (0.51) | DRD4DRD2DRD3POLBMEN1 | |
| SCHEMBL11096744 | 0.78 | UBE2M (0.45) | DRD4DRD2DRD3HPGDGAA | |
| SCHEMBL11098468 | 0.78 | TSHR (0.44) | DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |