Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095644 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTHPGDSMN1; SMN2 | |
| SCHEMBL11090150 | 0.88 | HPGD (0.45) | ALDH1A1MAPK1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11089190 | 0.88 | EPAS1 (0.48) | ALDH1A1MAPTSMN1; SMN2NPSR1NPC1 | |
| SCHEMBL11090842 | 0.86 | KMT2A (0.43) | ALDH1A1MAPTHPGDSMN1; SMN2NPSR1 | |
| SCHEMBL11093774 | 0.86 | EPAS1 (0.39) | ALDH1A1MAPK1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11095039 | 0.86 | CXCL8 (0.47) | ALDH1A1MAPK1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11089521 | 0.86 | CXCL8 (0.47) | ALDH1A1MAPK1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL11094346 | 0.84 | CAMK2A (0.50) | MAPTHPGDPTGDR2 | |
| SCHEMBL11096606 | 0.84 | CYP3A4 (0.44) | ALDH1A1NPSR1LMNACYP2D6SLC6A2 | |
| SCHEMBL28575436 | 0.83 | SLC6A2 (0.49) | ALDH1A1TSHRMAPK1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |