Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090150 | 0.88 | HPGD (0.45) | MAPTSMN1; SMN2NPSR1MAPK1HPGD | |
| SCHEMBL4296586 | 0.86 | NLRP3 (0.47) | MAPTSMN1; SMN2L3MBTL1NPSR1MAPK1 | |
| SCHEMBL11089521 | 0.86 | CXCL8 (0.47) | CXCL8MAPTSMN1; SMN2L3MBTL1NPSR1 | |
| SCHEMBL11089795 | 0.86 | ALDH1A1 (0.43) | MAPTSMN1; SMN2NPSR1MAPK1HPGD | |
| SCHEMBL11089527 | 0.85 | CXCL8 (0.46) | CXCL8MAPTSMN1; SMN2HSPB1L3MBTL1 | |
| SCHEMBL11092290 | 0.84 | CXCL8 (0.68) | CXCL8MAPTSMN1; SMN2HSPB1L3MBTL1 | |
| SCHEMBL11155097 | 0.83 | CXCL8 (0.51) | CXCL8MAPTSMN1; SMN2HSPB1L3MBTL1 | |
| SCHEMBL11089616 | 0.83 | ALDH1A1 (0.40) | CXCL8MAPTSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL11092614 | 0.81 | CXCL8 (0.51) | CXCL8L3MBTL1HPGDALDH1A1KMT2A | |
| SCHEMBL11095644 | 0.81 | ALDH1A1 (0.41) | MAPTSMN1; SMN2HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |