Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093774 | 0.90 | EPAS1 (0.39) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL11089795 | 0.90 | ALDH1A1 (0.43) | ALDH1A1SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL11089190 | 0.89 | EPAS1 (0.48) | ALDH1A1HTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11096606 | 0.88 | CYP3A4 (0.44) | ALDH1A1HTR2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11093624 | 0.86 | CHRM1 (0.50) | ALDH1A1GAASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11090842 | 0.85 | KMT2A (0.43) | ALDH1A1HTR2ASLC6A4MAPTLMNA | |
| SCHEMBL11089521 | 0.85 | CXCL8 (0.47) | ALDH1A1SLC6A4SLC6A2SLC6A3MAPT | |
| SCHEMBL11089397 | 0.84 | CHRM1 (0.46) | HTR2ASLC6A4SLC6A2SLC6A3PPARA | |
| SCHEMBL11089616 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TLR8MAPTLMNAHPGD | |
| SCHEMBL1146416 | 0.83 | HTR2A (0.54) | HTR2ASLC6A4SLC6A2SLC6A3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |