SCHEMBL11089885

SCHEMBL11089885

CCCC(c1ccccc1)N1C(=O)CNC1=O

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
OPRM1 P35372 6/20 0.45
OPRD1 P41143 6/20 0.45
OPRK1 P41145 6/20 0.45
OPRL1 P41146 6/20 0.45
GSK3A P49840 1/20 0.41
GSK3B P49841 1/20 0.41
CYP17A1 P05093 1/20 0.39
SLC6A4 P31645 6/20 0.37
SLC6A2 P23975 5/20 0.37
PKM P14618 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11082175 0.88 MEN1 (0.55) MEN1KMT2AOPRM1OPRD1OPRK1
SCHEMBL11090644 0.84 MEN1 (0.40) MEN1KMT2AOPRM1OPRD1OPRK1
SCHEMBL11082747 0.76 KMT2A (0.48) MEN1KMT2AOPRM1OPRD1OPRK1
SCHEMBL5145638 0.70 OPRM1 (0.47) MEN1KMT2AOPRM1OPRD1OPRK1
SCHEMBL10598753 0.67 OPRM1 (0.63) OPRM1OPRD1OPRK1OPRL1SLC6A4
SCHEMBL10413788 0.67 SLC6A4 (0.69) MEN1KMT2AOPRM1OPRD1OPRK1
SCHEMBL113896 0.66 CYP1A2 (0.62) OPRM1OPRD1OPRK1OPRL1SLC6A4
SCHEMBL10601133 0.66 CYP1A2 (0.62) OPRM1OPRD1OPRK1OPRL1SLC6A4
SCHEMBL7330913 0.66 GSK3A (0.59) MEN1KMT2AGSK3AGSK3B
SCHEMBL11402822 0.66 L3MBTL1 (0.40) MEN1KMT2AOPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4464387-A Insecticidal phenyl hydantoin compounds BUFFALO COLOR CORP. (US) 1984-08-07 US disclosed