SCHEMBL11082175

SCHEMBL11082175

CCC(c1ccccc1)N1C(=O)CNC1=O

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
OPRD1 P41143 5/20 0.43
OPRM1 P35372 4/20 0.43
OPRK1 P41145 4/20 0.43
OPRL1 P41146 4/20 0.43
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
HSD11B1 P28845 2/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SIGMAR1 Q99720 2/20 0.38
CYP17A1 P05093 1/20 0.36
BRPF1 P55201 1/20 0.36
KDM4C Q9H3R0 1/20 0.35
LMNA P02545 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11089885 0.88 MEN1 (0.52) MEN1KMT2AOPRD1OPRM1OPRK1
SCHEMBL11082747 0.78 KMT2A (0.48) MEN1KMT2AOPRD1OPRM1OPRK1
SCHEMBL28286235 0.74 LMNA (0.41) MEN1KMT2AOPRD1OPRM1OPRK1
SCHEMBL16118554 0.73 HSD11B1 (0.44) MEN1KMT2AOPRD1OPRM1OPRK1
SCHEMBL12898667 0.73 ALDH1A1 (0.52) LMNA
SCHEMBL11090644 0.72 MEN1 (0.40) MEN1KMT2AOPRD1OPRM1OPRK1
SCHEMBL13878052 0.70 ALDH1A1 (0.43) MEN1KMT2AOPRD1OPRM1OPRK1
SCHEMBL13349402 0.70 TSHR (0.34) MEN1KMT2AGSK3AGSK3BTSHR
SCHEMBL13923588 0.69 CASP3 (0.42) MEN1KMT2AOPRD1OPRM1OPRK1
SCHEMBL7330913 0.68 GSK3A (0.59) MEN1KMT2AGSK3AGSK3BBRPF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4464387-A Insecticidal phenyl hydantoin compounds BUFFALO COLOR CORP. (US) 1984-08-07 US disclosed