Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089885 | 0.84 | MEN1 (0.52) | MEN1KMT2AOPRM1RAB9AOPRD1 | |
| SCHEMBL7161876 | 0.77 | SLC6A2 (0.41) | HIF1ALMNAGALR3OPRM1DRD3 | |
| SCHEMBL11082175 | 0.72 | MEN1 (0.55) | MEN1KMT2ALMNAOPRM1TSHR | |
| SCHEMBL24384344 | 0.68 | OPRM1 (0.47) | HIF1ALMNAGALR3OPRM1DRD3 | |
| SCHEMBL5563575 | 0.67 | HIF1A (0.50) | HIF1ALMNAGALR3OPRM1DRD3 | |
| SCHEMBL11619633 | 0.67 | OPRM1 (0.54) | HIF1ALMNAGALR3OPRM1DRD3 | |
| SCHEMBL29378831 | 0.66 | KYNU (0.44) | HIF1ALMNAGALR3OPRM1DRD3 | |
| SCHEMBL15178086 | 0.66 | HIF1A (0.62) | MEN1KMT2AHIF1ALMNAGALR3 | |
| SCHEMBL4843327 | 0.66 | HIF1A (0.62) | MEN1KMT2AHIF1ALMNAGALR3 | |
| SCHEMBL6912280 | 0.66 | ADRB1 (0.50) | HIF1ALMNAGALR3OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464387-A | Insecticidal phenyl hydantoin compounds | BUFFALO COLOR CORP. (US) | 1984-08-07 | — | — | US | disclosed |