Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088655 | 0.84 | ACACB (0.41) | GRM2ACACBPPARGPPARDPPARA | |
| SCHEMBL11084088 | 0.81 | THRB (0.50) | GRM2ALDH1A1ACACBPPARGPPARD | |
| SCHEMBL5672844 | 0.72 | LDHA (0.59) | ALDH1A1ACACBPPARGPPARA | |
| SCHEMBL6970440 | 0.72 | CYP2D6 (0.48) | ALDH1A1CYP2D6NPC1HPGDRAB9A | |
| SCHEMBL6977414 | 0.72 | CYP2D6 (0.51) | ALDH1A1CYP2D6NPC1HPGDRAB9A | |
| SCHEMBL11078720 | 0.71 | ACACB (0.47) | ACACBPPARGPPARDPPARA | |
| SCHEMBL11078939 | 0.70 | MAPT (0.52) | ALDH1A1PPARGPPARAHPGD | |
| SCHEMBL9518399 | 0.69 | CYP2D6 (0.49) | ALDH1A1CYP2D6MAPK1SLC6A3 | |
| SCHEMBL12142816 | 0.69 | MAPT (0.46) | ALDH1A1CYP2D6SLC6A3 | |
| SCHEMBL11639674 | 0.68 | CYP2D6 (0.48) | ALDH1A1CYP2D6MAPK1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461902-A | BLOOD LIPID AND SUGAR LOWERING AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-07-24 | — | — | US | disclosed |
| EP-0084926-A1 | Thiazolidine derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-08-03 | — | — | EP | disclosed |