Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833941 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL11089977 | 0.85 | LMNA (0.46) | ALDH1A1TSHRLMNAGAANPC1 | |
| SCHEMBL9835846 | 0.81 | GAA (0.54) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL9835853 | 0.81 | GAA (0.54) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL11087777 | 0.77 | SMN1; SMN2 (0.49) | ALDH1A1TSHRGAANPC1TP53 | |
| SCHEMBL9834934 | 0.77 | CA1 (0.47) | ALDH1A1MEN1KMT2AGAANPC1 | |
| SCHEMBL9834922 | 0.77 | CA1 (0.47) | ALDH1A1MEN1KMT2AGAANPC1 | |
| SCHEMBL11092529 | 0.76 | LMNA (0.45) | ALDH1A1TSHRLMNAGAANPC1 | |
| SCHEMBL11092110 | 0.75 | NPC1 (0.45) | ALDH1A1TSHRMEN1KMT2ANPC1 | |
| SCHEMBL11055373 | 0.74 | NPC1 (0.44) | ALDH1A1TSHRMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | claimed |
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | disclosed |