Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.48 |
| ▸ | PRKCG | P05129 | 3/20 | 0.48 |
| ▸ | PRKCB | P05771 | 3/20 | 0.48 |
| ▸ | PRKCA | P17252 | 3/20 | 0.48 |
| ▸ | PRKCH | P24723 | 3/20 | 0.48 |
| ▸ | PRKCI | P41743 | 3/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.48 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.48 |
| ▸ | FDPS | P14324 | 5/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.35 |
| ▸ | LAP3 | P28838 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11087945 | 0.91 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11078067 | 0.91 | PRKD3 (0.56) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11090082 | 0.85 | ENPP2 (0.50) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11085675 | 0.84 | PRKD3 (0.50) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11087663 | 0.84 | PRKD3 (0.50) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11082142 | 0.84 | PRKD3 (0.43) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Phosphoric Acid SCHEMBL11089195 | 0.84 | SMPD1 (0.42) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11087685 | 0.83 | PRKCA (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9670759 | 0.83 | PRKCA (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL11083678 | 0.83 | PRKCA (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444766-A | ANTITUMOR | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-24 | — | — | US | disclosed |