Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11094919 | 0.91 | ADORA1 (0.45) | MAP4K4ADORA1ADORA2BL3MBTL1ADORA2A | |
| SCHEMBL11090534 | 0.85 | CTSS (0.49) | ADORA1ADORA2BADORA2APGK1GABRG2 | |
| SCHEMBL11085923 | 0.85 | CTSS (0.47) | ADORA1ADORA2BL3MBTL1ADORA2APGK1 | |
| SCHEMBL11093293 | 0.84 | ADORA1 (0.60) | MAP4K4ADORA1ADORA2BADORA2APGK1 | |
| SCHEMBL11090104 | 0.83 | ADORA1 (0.59) | ADORA1ADORA2BADORA2AUSP8HPGD | |
| SCHEMBL11096062 | 0.76 | CTSS (0.44) | ADORA1ADORA2BL3MBTL1ADORA2AUSP8 | |
| SCHEMBL11090728 | 0.76 | CTSS (0.46) | ADORA1ADORA2BL3MBTL1ADORA2AGABRG2 | |
| SCHEMBL11401495 | 0.76 | ADORA1 (0.50) | ADORA1ADORA2BL3MBTL1ADORA2ACHUK | |
| SCHEMBL11089932 | 0.76 | ERBB2 (0.47) | ADORA1ADORA2BADORA2APGK1USP8 | |
| SCHEMBL11087127 | 0.75 | ADORA1 (0.51) | MAP4K4ADORA1ADORA2BL3MBTL1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |