Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PGK1 | P00558 | 2/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090728 | 0.91 | CTSS (0.46) | CTSSCTSKGABRG2GABRB3GABRA5 | |
| SCHEMBL11085923 | 0.86 | CTSS (0.47) | CTSSCTSKGABRG2GABRB3GABRA5 | |
| SCHEMBL11090451 | 0.85 | MAP4K4 (0.48) | GABRG2GABRB3GABRA5GABRA3ADORA1 | |
| SCHEMBL11093293 | 0.85 | ADORA1 (0.60) | CTSSCTSKADORA1ADORA2AADORA2B | |
| SCHEMBL11090104 | 0.84 | ADORA1 (0.59) | ADORA1ADORA2AADORA2BSMN1; SMN2KDM4E | |
| SCHEMBL11094028 | 0.80 | PIP4K2A (0.44) | CTSSCTSKADORA1ADORA2AADORA2B | |
| SCHEMBL11096062 | 0.77 | CTSS (0.44) | CTSSCTSKADORA1ADORA2AADORA2B | |
| SCHEMBL11089932 | 0.77 | ERBB2 (0.47) | ADORA1ADORA2AADORA2BSMN1; SMN2KDM4E | |
| SCHEMBL11094919 | 0.76 | ADORA1 (0.45) | GABRG2GABRB3GABRA5GABRA3ADORA1 | |
| SCHEMBL11087127 | 0.76 | ADORA1 (0.51) | CTSSCTSKADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460403-A | 2,3-Dicyano 6 phenyl pyrazine herbicides | KYOWA GAS CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4259489-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | KYOWA GAS CHEMICAL INDUSTRY CO. LTD. (JP) | 1981-03-31 | — | — | US | disclosed |