Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138445 | 0.84 | MAPT (0.51) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL13185886 | 0.79 | GAA (0.70) | GAAALDH1A1CA2CA9MAPT | |
| SCHEMBL28788611 | 0.79 | MAPT (0.46) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL20334822 | 0.77 | GAA (0.49) | GAAALDH1A1CA2CA9MAPT | |
| SCHEMBL2093805 | 0.76 | MAPT (0.48) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL5250150 | 0.74 | LMNA (0.50) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL49648 | 0.73 | MAPT (0.54) | GAAALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL21820734 | 0.73 | PKM (0.42) | GAAKMT2AACACBRAB9ACTSK | |
| SCHEMBL26746 | 0.72 | SLC6A2 (0.44) | ALDH1A1CA2CA9MAPTMEN1 | |
| SCHEMBL11167613 | 0.71 | HTT (0.58) | GAAALDH1A1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034253-B1 | 4-TERT.-BUTOXY-PHENYL-GLYCINE NITRILE, AND PROCESS FOR THE PREPARATION OF D-(-)- AND L-(+)-4-HYDROXY-PHENYL GLYCINE | BASF Aktiengesellschaft (DE) | 1984-07-18 | — | — | EP | disclosed |
| EP-0034253-B1 | 4-TERT.-BUTOXY-PHENYL-GLYCINE NITRILE, AND PROCESS FOR THE PREPARATION OF D-(-)- AND L-(+)-4-HYDROXY-PHENYL GLYCINE | BASF Aktiengesellschaft (DE) | 1984-07-18 | — | — | EP | disclosed |
| US-4350641-A | 4-Tert.-butoxyphenylglycinonitrile and the preparation of D-(-)- and L-(+)-4-hydroxyphenylglycine | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| EP-0034253-A2 | 4-Tert.-butoxy-phenyl-glycine nitrile, and process for the preparation of D-(-)- and L-(+)-4-hydroxy-phenyl glycine | BASF Aktiengesellschaft (DE) | 1981-08-26 | — | — | EP | disclosed |