Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL9416770 | 0.89 | ALDH1A1 (0.48) | KMT2AMEN1RECQLLMNAKDM4E | |
| Chlorobenzene SCHEMBL11092864 | 0.80 | TSHR (0.52) | KMT2AMEN1CES2CES1EGFR | |
| SCHEMBL11082334 | 0.79 | FLT1 (0.48) | KMT2AMEN1FLT1FLT4KDR | |
| Toluene SCHEMBL9416863 | 0.78 | LMNA (0.50) | KMT2AMEN1CES2CES1LMNA | |
| SCHEMBL27668009 | 0.78 | CES2 (0.54) | KMT2AMEN1CES2CES1EGFR | |
| Toluene SCHEMBL761209 | 0.78 | LMNA (0.50) | KMT2AMEN1CES2CES1LMNA | |
| SCHEMBL6543723 | 0.77 | CES2 (0.56) | KMT2AMEN1CES2CES1EGFR | |
| 1,4-Dichlorobenzene SCHEMBL29046429 | 0.77 | LMNA (0.53) | KMT2ACES2CES1EGFRERBB2 | |
| SCHEMBL5314183 | 0.77 | LMNA (0.53) | KMT2ACES2CES1EGFRERBB2 | |
| Methyl Alcohol SCHEMBL28164649 | 0.74 | CES2 (0.64) | KMT2AMEN1CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129182-A1 | Arylsulfonyl hydrazones as blowing agents | BAYER AG (DE) | 1984-12-27 | — | — | EP | disclosed |