Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15759290 | 0.87 | LTA4H (0.46) | ALDH1A1SAE1UBA2LTA4HHTT | |
| SCHEMBL11073700 | 0.83 | CHRM2 (0.46) | ALDH1A1CMA1HTTMMP13 | |
| SCHEMBL1702302 | 0.81 | HTT (0.48) | KCNA3USP2ALDH1A1LTA4HHTT | |
| Ethylene SCHEMBL11075789 | 0.81 | CHRM2 (0.43) | ALDH1A1CMA1HTTMMP13 | |
| SCHEMBL11092391 | 0.77 | ALDH1A1 (0.43) | KCNA3F2RL1GAAHSD11B1ALDH1A1 | |
| SCHEMBL11096449 | 0.75 | KCNA3 (0.46) | KCNA3F2RL1ALDH1A1HTTNR3C1 | |
| SCHEMBL11088581 | 0.75 | ALDH1A1 (0.42) | KCNA3F2RL1GAAHSD11B1ALDH1A1 | |
| SCHEMBL11091173 | 0.73 | OPRM1 (0.55) | KCNA3HSD11B1ALDH1A1GRIN1GRIN2A | |
| SCHEMBL11092707 | 0.72 | CRBN (0.39) | KCNA3F2RL1GAAHSD11B1USP2 | |
| SCHEMBL3561618 | 0.72 | ALDH1A1 (0.43) | KCNA3GAAUSP2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | claimed |
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |