Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474185 | 0.79 | CYP1A2 (0.39) | KMT2AKDM4ERAB9AADRB2PKM | |
| SCHEMBL11086422 | 0.78 | GAA (0.40) | GAAKMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL17445904 | 0.78 | PDK2 (0.46) | KMT2AKDM4EALDH1A1RAB9APKM | |
| SCHEMBL11094297 | 0.77 | PDK2 (0.45) | GAAKMT2AKDM4ENPC1RAB9A | |
| SCHEMBL11092218 | 0.77 | KDM4E (0.35) | KMT2AKDM4EALDH1A1RAB9APKM | |
| SCHEMBL11092216 | 0.77 | KDM4E (0.35) | KMT2AKDM4EALDH1A1RAB9APKM | |
| SCHEMBL11205330 | 0.77 | SIGMAR1 (0.45) | KMT2AKDM4EALDH1A1HTTPKM | |
| SCHEMBL11211789 | 0.75 | SIGMAR1 (0.56) | ADRB2 | |
| SCHEMBL11089092 | 0.75 | MTTP (0.43) | GAAKMT2AALDH1A1HTT | |
| SCHEMBL10778233 | 0.74 | ALDH1A1 (0.36) | KMT2AKDM4EALDH1A1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452745-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4382093-A | 9-Aminoalkylfluorenes | ELI LILLY AND COMPANY (US) | 1983-05-03 | — | — | US | disclosed |
| US-4277495-A | FLUORENE 9-AMINOALKYL-9-CARBOXYLIC ACIDS OR ESTERS | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |