Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128892 | 0.76 | HTT (0.75) | HTTMAPTKMT2APKMPOLB | |
| SCHEMBL11032375 | 0.74 | KDM4E (0.54) | TSHRHTTMAPTKMT2AGRM5 | |
| SCHEMBL11445405 | 0.73 | TSHR (0.61) | TSHRHTTMAPTKMT2APOLB | |
| SCHEMBL11095432 | 0.72 | MAPT (0.50) | HTTMAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL11092528 | 0.69 | ALDH1A1 (0.51) | TSHRHTTMAPTKMT2APOLB | |
| SCHEMBL10339705 | 0.68 | KDM4E (0.50) | TSHRHTTMAPTKMT2APOLB | |
| SCHEMBL11087620 | 0.68 | KDM4E (0.50) | TSHRHTTMAPTKMT2APOLB | |
| SCHEMBL11087354 | 0.68 | NPC1 (0.53) | HTTMAPTKMT2AGRM5SMN1; SMN2 | |
| SCHEMBL11091998 | 0.67 | LMNA (0.49) | TSHRHTTMAPTKMT2APKM | |
| SCHEMBL11087676 | 0.67 | MAPT (0.59) | TSHRHTTMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |