Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087340 | 0.89 | SMN1; SMN2 (0.40) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL11084724 | 0.80 | ALDH1A1 (0.45) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL11114430 | 0.76 | GABRP (0.39) | KMT2AMEN1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11084301 | 0.74 | ALDH1A1 (0.40) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL11084270 | 0.72 | MEN1 (0.37) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL11083402 | 0.71 | CSNK2A1 (0.42) | KMT2AMAPTMEN1RAB9AEGFR | |
| SCHEMBL7276545 | 0.71 | GABRP (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11080774 | 0.70 | NPC1 (0.42) | KMT2AMAPTMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL11086602 | 0.68 | ALDH1A1 (0.41) | KMT2AMAPTMEN1RAB9AEGFR | |
| SCHEMBL11084914 | 0.67 | KDR (0.46) | MAPTRAB9ASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126970-A2 | Anxiolytic and anti-depressant thienopyridine derivatives | BEECHAM GROUP PLC (GB) | 1984-12-05 | — | — | EP | disclosed |