Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114430 | 0.83 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9837120 | 0.81 | KDM4E (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4904323 | 0.81 | AKR1C3 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27262833 | 0.76 | MAPT (0.49) | ALDH1A1PKMRXFP1LMNANPSR1 | |
| SCHEMBL11094914 | 0.74 | CSNK2A2 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11087340 | 0.74 | SMN1; SMN2 (0.40) | ALDH1A1RXFP1LMNAMAPK1LDHA | |
| SCHEMBL11092541 | 0.71 | KMT2A (0.40) | ALDH1A1LMNAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL4543435 | 0.70 | GPR35 (0.41) | ALDH1A1RXFP1MAPK1NPSR1KDM4E | |
| SCHEMBL8972231 | 0.69 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12786944 | 0.68 | ALDH1A1 (0.49) | ALDH1A1PKMMAPK1NPSR1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560348-B1 | Thieno 3,2-b pyridine derivatives for the treatment of gastrointestinal disorders | MITSUBISHI CHEM CORP (JP) | 2002-07-10 | — | — | EP | disclosed |
| US-5352685-A | Gastrointestinal disorders | MITSUBISHI KASEI CORPORATION (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0560348-A1 | Thieno 3,2-b pyridine derivatives for the treatment of gastrointestinal disorders | Mitsubishi Chemical Corporation (JP) | 1993-09-15 | — | — | EP | disclosed |
| CN-1019491-B | PREPAPARATION OF THIOPHENE-PYRIDONE USED AS NEW THERAPEUTIC AGENTS | BOOTS CO PLC (GB) | 1992-12-16 | — | — | CN | disclosed |
| CN-87107975-A | The preparation method of medicine | — | 1988-06-01 | — | — | CN | disclosed |